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When is Sirt1 activity bad for dying neurons?
Sirt1, the class III histone deacetylase, is generally associated with increased life span and with a pro-survival effect in neurons stressed by pathological factors. Recent work, however, suggests that Sirt1 silencing could also promote neuronal survival. A possible reason suggested is Sirt1 silenc...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3807049/ https://ncbi.nlm.nih.gov/pubmed/24167473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2013.00186 |
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