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Systemic morphine treatment induces changes in firing patterns and responses of nociceptive afferent fibers in mouse glabrous skin

Patients receiving opioids for pain may experience decreased effectiveness of the drug and even abnormal pain sensitivity – either hyperalgesia and/or allodynia. We hypothesize that peripheral nociceptor hyperexcitability contributes to opioid-induced hyperalgesia and test this using an in vitro mou...

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Autors principals: Hogan, Dale, Baker, Alyssa L., Morón, Jose A., Carlton, Susan M.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806901/
https://ncbi.nlm.nih.gov/pubmed/23711478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2013.05.033
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