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A stable human-derived packaging cell line for production of high titer retrovirus/vesicular stomatitis virus G pseudotypes.

We have generated a human 293-derived retroviral packaging cell line (293GPG) capable of producing high titers of recombinant Moloney murine leukemia virus particles that have incorporated the vesicular stomatitis virus G (VSV-G) protein. To achieve expression of the retroviral gag-pol polyprotein,...

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Huvudupphovsmän: Ory, D S, Neugeboren, B A, Mulligan, R C
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1996
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC38069/
https://ncbi.nlm.nih.gov/pubmed/8876147
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