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Architecture of the Atg17 Complex as a Scaffold for Autophagosome Biogenesis

Macroautophagy is a bulk clearance mechanism in which the double-membraned phagophore grows and engulfs cytosolic material. In yeast, the phagophore nucleates from a cluster of 20-30 nm diameter Atg9-containing vesicles located at a multiprotein assembly known as the preautophagosomal structure (PAS...

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Detalhes bibliográficos
Main Authors: Ragusa, Michael J., Stanley, Robin E., Hurley, James H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806636/
https://ncbi.nlm.nih.gov/pubmed/23219485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.11.028
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