Rhein Protects Pancreatic β-Cells From Dynamin-Related Protein-1–Mediated Mitochondrial Fission and Cell Apoptosis Under Hyperglycemia

Rhein, an anthraquinone compound isolated from rhubarb, has been shown to improve glucose metabolism disorders in diabetic mice. The mechanism underlying the protective effect of rhein, however, remains unknown. Here, we demonstrate that rhein can protect the pancreatic β-cells against hyperglycemia...

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Hlavní autoři: Liu, Jing, Chen, Zhaohong, Zhang, Yujing, Zhang, Mingchao, Zhu, Xiaodong, Fan, Yun, Shi, Shaolin, Zen, Ke, Liu, Zhihong
Médium: Artigo
Jazyk:Inglês
Vydáno: American Diabetes Association 2013
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Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806614/
https://ncbi.nlm.nih.gov/pubmed/23919963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0251
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