Protective Effects of Necrostatin-1 against Concanavalin A-Induced Acute Hepatic Injury in Mice

Objective. Necrostatin-1 (Nec-1) inhibits receptor-interacting protein 1 (RIP1) kinase and programmed necrosis. This study was designed to examine the protective effects and mechanisms of Nec-1 in concanavalin A- (ConA-) induced hepatitis in mice. Methods. C57BL/6 mice were exposed to ConA via tail...

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Detalhes bibliográficos
Principais autores: Zhou, Yingqun, Dai, Weiqi, Lin, Chunlei, Wang, Fan, He, Lei, Shen, Miao, Chen, Ping, Wang, Chenfen, Lu, Jie, Xu, Ling, Xu, Xuanfu, Guo, Chuanyong
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806455/
https://ncbi.nlm.nih.gov/pubmed/24198446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/706156
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