Exploring the Nicotinic Acetylcholine Receptor-associated Proteome with iTRAQ and Transgenic Mice

Neuronal nicotinic acetylcholine receptors (nAChRs) containing α4 and β2 subunits are the principal receptors in the mammalian central nervous system that bind nicotine with high affinity. These nAChRs are involved in nicotine dependence, mood disorders, neurodegeneration and neuroprotection. Howeve...

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Bibliographic Details
Main Authors: McClure-Begley, Tristan D., Stone, Kathy L., Marks, Michael J., Grady, Sharon R., Colangelo, Christopher M., Lindstrom, Jon M., Picciotto, Marina R.
Format: Artigo
Language:Inglês
Published: Elsevier 2013
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806329/
https://ncbi.nlm.nih.gov/pubmed/23891776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.gpb.2013.05.005
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