Therapeutic activity of inhibition of the soluble epoxide hydrolase in a mouse model of scrapie

AIMS: The misfolding and the aggregation of specific proteins are key features of neurodegenerative diseases, specifically Transmissible Spongiform Encephalopathies (TSEs). In TSEs, neuronal loss and inflammation are associated with the accumulation of the misfolded isoform (PrP(sc)) of the cellular...

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Hauptverfasser: Poli, Giorgio, Corda, Erica, Martino, Piera Anna, Dall’Ara, Paola, Bareggi, Silvio R., Bondiolotti, Giampietro, Iulini, Barbara, Mazza, Maria, Casalone, Cristina, Hwang, Sung Hee, Hammock, Bruce D., Inceoglu, Bora
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806320/
https://ncbi.nlm.nih.gov/pubmed/23651659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2013.04.014
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