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Therapeutic activity of inhibition of the soluble epoxide hydrolase in a mouse model of scrapie

AIMS: The misfolding and the aggregation of specific proteins are key features of neurodegenerative diseases, specifically Transmissible Spongiform Encephalopathies (TSEs). In TSEs, neuronal loss and inflammation are associated with the accumulation of the misfolded isoform (PrP(sc)) of the cellular...

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Detalhes bibliográficos
Main Authors: Poli, Giorgio, Corda, Erica, Martino, Piera Anna, Dall’Ara, Paola, Bareggi, Silvio R., Bondiolotti, Giampietro, Iulini, Barbara, Mazza, Maria, Casalone, Cristina, Hwang, Sung Hee, Hammock, Bruce D., Inceoglu, Bora
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806320/
https://ncbi.nlm.nih.gov/pubmed/23651659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.lfs.2013.04.014
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