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Direct Tandem Mass Spectrometric Profiling of Sulfatides in Dry Urinary Samples for Screening of Metachromatic Leukodystrophy

BACKGROUND: Prediagnostic steps in suspected metachromatic leukodystrophy (MLD) rely onclinical chemical methods other than enzyme assays. We report a new diagnostic method which evaluates changes in the spectrum of molecular types of sulfatides (3-O-sulfogalactosyl ceramides) in MLD urine. METHODS:...

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Detaylı Bibliyografya
Asıl Yazarlar: Kuchař, Ladislav, Asfaw, Befekadu, Poupětová, Helena, Honzíková, Jitka, Tureček, František, Ledvinová, Jana
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806293/
https://ncbi.nlm.nih.gov/pubmed/23838369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cca.2013.06.027
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