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Combination with Methotrexate and Cyclophosphamide Attenuated Maturation of Dendritic Cells: Inducing Treg Skewing and Th17 Suppression In Vivo

Immune disorder is considered the main pathogenesis of autoimmune diseases, such as rheumatoid arthritis (RA). The balance of the two special subsets of CD4(+)T cells, T helper cell 17 (Th17), and Regulator T cell (Treg) is the key factor of maintaining a normal immune response. Dendritic cells (DCs...

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Detalhes bibliográficos
Main Authors: Yu, Xiaoyang, Wang, Caihong, Luo, Jing, Zhao, Xiangcong, Wang, Lixing, Li, Xiaofeng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3806152/
https://ncbi.nlm.nih.gov/pubmed/24194771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/238035
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