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Sirtuin Deacetylases as Therapeutic Targets in the Nervous System

Sirtuins are a conserved family of deacetylases whose activities are dependent on nicotinamide adenine dinucleotide (NAD(+)). Sirtuins act in different cellular compartments, such as the nucleus where they deacetylate histones and transcriptional factors, in the cytoplasm where they modulate cytoske...

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Detalhes bibliográficos
Main Authors: Langley, Brett, Sauve, Anthony
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805877/
https://ncbi.nlm.nih.gov/pubmed/24037427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13311-013-0214-5
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