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Next-generation sequencing of endoscopic biopsies identifies ARID1A as a tumor-suppressor gene in Barrett’s esophagus

The incidence of Barrett’s esophagus (BE)-associated esophageal adenocarcinoma (EAC) is increasing. Next-generation sequencing (NGS) provides an unprecedented opportunity to uncover genomic alterations during BE pathogenesis and progression to EAC, but treatment-naive surgical specimens are scarce....

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Библиографические подробности
Главные авторы: Streppel, MM, Lata, S, DelaBastide, M, Montgomery, EA, Wang, JS, Canto, MI, Macgregor-Das, AM, Pai, S, Morsink, FHM, Offerhaus, GJ, Antoniou, E, Maitra, A, McCombie, WR
Формат: Artigo
Язык:Inglês
Опубликовано: 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805724/
https://ncbi.nlm.nih.gov/pubmed/23318448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.586
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