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Human cytomegalovirus US3 impairs transport and maturation of major histocompatibility complex class I heavy chains.

The human cytomegalovirus (HCMV) early glycoprotein products of the US11 and US2 open reading frames cause increased turnover of major histocompatibility complex (MHC) class I heavy chains. Since US2 is homologous to another HCMV gene (US3), we hypothesized that the US3 gene product also may affect...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Jones, T R, Wiertz, E J, Sun, L, Fish, K N, Nelson, J A, Ploegh, H L
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38057/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8876135/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.21.11327
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