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Powerful Haplotype-Based Hardy-Weinberg Equilibrium Tests for Tightly Linked Loci

Recently, there have been many case-control studies proposed to test for association between haplotypes and disease, which require the Hardy-Weinberg equilibrium (HWE) assumption of haplotype frequencies. As such, haplotype inference of unphased genotypes and development of haplotype-based HWE tests...

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Main Authors: Mao, Wei-Gao, He, Hai-Qiang, Xu, Yan, Chen, Ping-Yan, Zhou, Ji-Yuan
格式: Artigo
語言:Inglês
出版: Public Library of Science 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805574/
https://ncbi.nlm.nih.gov/pubmed/24167573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077399
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