Methadone, QTc interval prolongation and torsade de pointes: Case reports offer the best understanding of this problem

We reviewed the literature and found 31 adult cases and 1 newborn case of methadone-associated QTc interval prolongation and/or torsade de pointes (TdP). Parametric statistics may not be useful in studying this issue because methadone-associated TdP is a very rare event and, hence, “an extreme outli...

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Autori principali: Vieweg, W. Victor R., Hasnain, Mehrul, Howland, Robert H., Clausen, Thomas, Koneru, Jayanthi N., Kogut, Christopher, Crouse, Ericka L. Breden, Hancox, Jules C., Fernandez, Antony, Pandurangi, Ananda K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: SAGE Publications 2013
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Reviews
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805428/
https://ncbi.nlm.nih.gov/pubmed/24167694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2045125312469982
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