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Evidence for Efficient Vertical Transfer of Maternal HIV-1 Envelope-Specific Neutralizing Antibodies but No Association of Such Antibodies with Reduced Infant Infection

Little is known about the efficiency of vertical transfer of HIV-1-specific antibodies. We compared antibody levels in plasma from 60 mother-infant pairs near the time of birth, including 14 breastfeeding transmission pairs. The Envelope binding titers were strongly correlated (r=0.91, p<0.0001)...

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Detalhes bibliográficos
Main Authors: Omenda, Maxwel M., Milligan, Caitlin, Odem-Davis, Katherine, Nduati, Ruth, Richardson, Barbra A., Lynch, John, John-Stewart, Grace, Overbaugh, Julie
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805370/
https://ncbi.nlm.nih.gov/pubmed/23774880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0b013e31829f6e41
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