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Older HIV-infected patients on antiretroviral therapy have B-cell expansion and attenuated CD4 cell increases with immune activation reduction

BACKGROUND: The contribution of immune activation to accelerated HIV-disease progression in older individuals has not been delineated. METHODS: Prospective multicenter cohort of older (≥45 years) and younger (18–30 years) HIV-infected adults initiating 192 weeks of antiretroviral therapy (ART). Long...

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Main Authors: Kalayjian, Robert C., Spritzler, John, Matining, Roy M., Fiscus, Susan A., Gross, Barry H., Francis, Isaac R., Pollard, Richard B., Lederman, Michael M., Landay, Alan
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805132/
https://ncbi.nlm.nih.gov/pubmed/24047762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAD.0b013e32835fabc2
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