Molecular Characterization of Pediatric Gastrointestinal Stromal Tumors

PURPOSE: Pediatric gastrointestinal stromal tumors (GIST) are rare and occur preferentially in females as multifocal gastric tumors, typically lacking mutations in KIT and PDGFRA. As KIT oncoprotein is consistently overexpressed in pediatric GIST, we sought to investigate the activation of KIT downs...

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Autores principales: Agaram, Narasimhan P., Laquaglia, Michael P., Ustun, Berrin, Guo, Tianhua, Wong, Grace C., Socci, Nicholas D., Maki, Robert G., DeMatteo, Ronald P., Besmer, Peter, Antonescu, Cristina R.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3805121/
https://ncbi.nlm.nih.gov/pubmed/18483389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-07-1984
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