A common rejection module (CRM) for acute rejection across multiple organs identifies novel therapeutics for organ transplantation

Using meta-analysis of eight independent transplant datasets (236 graft biopsy samples) from four organs, we identified a common rejection module (CRM) consisting of 11 genes that were significantly overexpressed in acute rejection (AR) across all transplanted organs. The CRM genes could diagnose AR...

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Detalhes bibliográficos
Main Authors: Khatri, Purvesh, Roedder, Silke, Kimura, Naoyuki, De Vusser, Katrien, Morgan, Alexander A., Gong, Yongquan, Fischbein, Michael P., Robbins, Robert C., Naesens, Maarten, Butte, Atul J., Sarwal, Minnie M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804941/
https://ncbi.nlm.nih.gov/pubmed/24127489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20122709
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