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The biophysical and molecular basis of intracellular pH sensing by Na(+)/H(+) exchanger-3
Epithelial Na(+)/H(+) exchanger-3 (NHE3) transport is fundamental for renal and intestinal sodium reabsorption. Cytoplasmic protons are thought to serve as allosteric modifiers of the exchanger and to trigger its transport through protein conformational change. This effect presupposes an intracellul...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Federation of American Societies for Experimental Biology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3804747/ https://ncbi.nlm.nih.gov/pubmed/23934281 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.12-225466 |
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