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Immunogenicity of Rabies Virus Inactivated by β-Propiolactone, Acetylethyleneimine, and Ionizing Irradiation

Ionizing radiation, β-propiolactone, and acetylethyleneimine were compared for their ability as virus-inactivating agents for the preparation of rabies vaccine. Each agent reduced viral infectivity exponentially; ionizing radiation also destroyed viral hemagglutinin. The vaccine prepared by ionizing...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Appl Microbiol
Hauptverfasser: Wiktor, T. J., Aaslestad, H. G., Kaplan, M. M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1972
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC380470/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/5031561/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/am.23.5.914-918.1972
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