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Can K-ras Gene Mutation Be Utilized as Prognostic Biomarker for Colorectal Cancer Patients Receiving Chemotherapy? A Meta-Analysis and Systematic Review

INTRODUCTION: K-ras gene mutations were common in colorectal patients, but their relationship with prognosis was unclear. OBJECTIVE: Verify prognostic differences between patient with and without mutant K-ras genes by reviewing the published evidence. METHOD: Systematic reviews and data bases were s...

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Detalhes bibliográficos
Main Authors: Rui, Yuan-Yi, Zhang, Dan, Zhou, Zong-Guang, Wang, Cun, Yang, Lie, Yu, Yong-Yang, Chen, Hai-Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804628/
https://ncbi.nlm.nih.gov/pubmed/24205021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077901
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