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PTCH1 Gene Mutations in Keratocystic Odontogenic Tumors: A Study of 43 Chinese Patients and a Systematic Review

BACKGROUND: The keratocystic odontogenic tumor (KCOT) is a locally aggressive cystic jaw lesion that occurs sporadically or in association with nevoid basal cell carcinoma syndrome (NBCCS). PTCH1, the gene responsible for NBCCS, may play an important role in sporadic KCOTs. In this study, we analyze...

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Detalhes bibliográficos
Main Authors: Guo, Yan-Yan, Zhang, Jian-Yun, Li, Xue-Fen, Luo, Hai-Yan, Chen, Feng, Li, Tie-Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804548/
https://ncbi.nlm.nih.gov/pubmed/24204797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0077305
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