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Physiological coupling of growth factor and steroid receptor signaling pathways: estrogen receptor knockout mice lack estrogen-like response to epidermal growth factor.

Past studies have shown that epidermal growth factor (EGF) is able to mimic the uterotropic effects of estrogen in the rodent. These studies have suggested a "cross-talk" model in which EGF receptor (EGF-R) signaling results in activation of nuclear estrogen receptor (ER) and its target genes in an...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Curtis, S W, Washburn, T, Sewall, C, DiAugustine, R, Lindzey, J, Couse, J F, Korach, K S
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38043/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8901633/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.22.12626
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