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B Lymphocytes: Development, Tolerance, and Their Role in Autoimmunity—Focus on Systemic Lupus Erythematosus

B lymphocytes are the effectors of humoral immunity, providing defense against pathogens through different functions including antibody production. B cells constitute approximately 15% of peripheral blood leukocytes and arise from hemopoietic stem cells in the bone marrow. It is here that their anti...

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Bibliographic Details
Main Authors: Tobón, Gabriel J., Izquierdo, Jorge H., Cañas, Carlos A.
Format: Artigo
Language:Inglês
Published: Hindawi Publishing Corporation 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804284/
https://ncbi.nlm.nih.gov/pubmed/24187614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/827254
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