ET(A) receptor specific stimulation of glomerular inflammation and injury in streptozotocin-induced diabetic rats

AIMS/HYPOTHESIS: ET(A) receptor activation increases glomerular permeability to albumin (P(alb)) and elevates pre-inflammatory markers in hyperglycaemic (HG) rats. METHODS: Male Sprague-Dawley rats were given streptozotocin (STZ), n=32 or saline (sham,), n=32. Half of the animals in each group recei...

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Bibliografiske detaljer
Main Authors: Saleh, M. A., Boesen, E. I., Pollock, J. S., Savin, V. J., Pollock, D. M.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804244/
https://ncbi.nlm.nih.gov/pubmed/21191784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-010-2021-4
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