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Optogenetic Inhibition of Synaptic Release with Chromophore-Assisted Light Inactivation (CALI)

Optogenetic techniques provide effective ways of manipulating the functions of selected neurons with light. In the current study, we engineered an optogenetic technique that directly inhibits neurotransmitter release. We used a genetically encoded singlet oxygen generator, miniSOG, to conduct chromo...

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Detalhes bibliográficos
Main Authors: Lin, John Y., Sann, Sharon B., Zhou, Keming, Nabavi, Sadegh, Proulx, Christophe D., Malinow, Roberto, Jin, Yishi, Tsien, Roger Y.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804158/
https://ncbi.nlm.nih.gov/pubmed/23889931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.05.022
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