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Atomic Force Microscopy captures folded ribosome bound nascent chains

Direct visualization of co-translational folding of nascent polypeptide chains is challenging. Here we present, for the first time, AFM images of large protein constructs based on the membrane binding domain of ankyrin-R, complexed with the ribosome. The characteristic “horse-shoe” shape of ankyrin-...

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Bibliografski detalji
Glavni autori: Loksztejn, Anna, Scholl, Zackary, Marszalek, Piotr E.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3804001/
https://ncbi.nlm.nih.gov/pubmed/23051696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cc35551e
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