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Atomic Force Microscopy captures folded ribosome bound nascent chains
Direct visualization of co-translational folding of nascent polypeptide chains is challenging. Here we present, for the first time, AFM images of large protein constructs based on the membrane binding domain of ankyrin-R, complexed with the ribosome. The characteristic “horse-shoe” shape of ankyrin-...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3804001/ https://ncbi.nlm.nih.gov/pubmed/23051696 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2cc35551e |
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