Antiviral Activity of a bis-Benzimidazole Against Experimental Rhinovirus Infections in Chimpanzees

The marked antiviral activity of (S,S-1,2-bis(5-methoxy-2-benzimidazolyl)-1,2-ethanediol (Abbott 36683) against rhinoviruses in tissue culture warranted investigation of its antiviral activity in vivo. Antiviral levels in mouse sera were attained with an oral dose as small as 10 mg/kg and detectable...

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Bibliografische Detailangaben

Veröffentlicht in:	Appl Microbiol
Hauptverfasser:	Shipkowitz, N. L., Bower, R. R., Schleicher, J. B., Aquino, F., Appell, R. N., Roderick, W. R.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1972
Schlagworte:	Clinical Microbiology, Virology, and Immunology
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC380288/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4333893/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/am.23.1.117-122.1972
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