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Alternatively spliced mRNAs predicted to yield frame-shift proteins and stable intron 1 RNAs of the herpes simplex virus 1 regulatory gene alpha 0 accumulate in the cytoplasm of infected cells.

The infected cell protein no. 0 (ICP0), the product of the alpha 0 gene, and an important herpes simplex virus 1 regulatory protein is encoded by three exons. We report that intron 1 forms a family of four stable nonpolyadenylylated cytoplasmic RNAs sharing a common 5' end but differing in 3' ends....

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Carter, K L, Roizman, B
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38027/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8901617/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.22.12535
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