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A tumor-selective somatostatin analog (TT-232) with strong in vitro and in vivo antitumor activity.

We report a series of new in vitro and in vivo data proving the selective antitumor activity of our somatostatin structural derivative, TT-232. In vitro, it inhibited the proliferation of 20 different human tumor cell lines in the range of 50-95% and induced a very strong apoptosis. In vivo TT-232 w...

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Détails bibliographiques
Auteurs principaux: Kéri, G, Erchegyi, J, Horváth, A, Mezõ, I, Idei, M, Vántus, T, Balogh, A, Vadász, Z, Bökönyi, G, Seprõdi, J, Teplán, I, Csuka, O, Tejeda, M, Gaál, D, Szegedi, Z, Szende, B, Roze, C, Kalthoff, H, Ullrich, A
Format: Artigo
Langue:Inglês
Publié: 1996
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC38023/
https://ncbi.nlm.nih.gov/pubmed/8901613
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