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Cotransfection of Pax2 and Math1 promote in situ cochlear hair cell regeneration after neomycin insult

The ideal strategy for hair cell regeneration is promoting residual supporting cell proliferation followed by induction of hair cell differentiation. In this study, cultured neonatal mouse organs of Corti were treated with neomycin to eliminate hair cells followed by incubation with recombined adeno...

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Main Authors: Chen, Yan, Yu, Huiqian, Zhang, Yanping, Li, Wen, Lu, Na, Ni, Wenli, He, Yingzi, Li, Jin, Sun, Shan, Wang, Zhengmin, Li, Huawei
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2013
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801138/
https://ncbi.nlm.nih.gov/pubmed/24141260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep02996
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