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Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China
The 2-hydroxyglutarate (2-HG) has been reported to result from mutations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) genes and to function as an “oncometabolite.” To evaluate the clinical significance of serum 2-HG levels in hematologic malignancies, acute myeloid leukemia (AML) in particula...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3801077/ https://ncbi.nlm.nih.gov/pubmed/24082129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315558110 |
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