Prognostic significance of 2-hydroxyglutarate levels in acute myeloid leukemia in China

The 2-hydroxyglutarate (2-HG) has been reported to result from mutations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) genes and to function as an “oncometabolite.” To evaluate the clinical significance of serum 2-HG levels in hematologic malignancies, acute myeloid leukemia (AML) in particula...

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Autori principali: Wang, Jiang-Han, Chen, Wen-Lian, Li, Jun-Min, Wu, Song-Fang, Chen, Tian-Lu, Zhu, Yong-Mei, Zhang, Wei-Na, Li, Yang, Qiu, Yun-Ping, Zhao, Ai-Hua, Mi, Jian-Qing, Jin, Jie, Wang, Yun-Gui, Ma, Qiu-Ling, Huang, He, Wu, De-Pei, Wang, Qin-Rong, Li, Yan, Yan, Xiao-Jing, Yan, Jin-Song, Li, Jian-Yong, Wang, Shuai, Huang, Xiao-Jun, Wang, Bing-Shun, Jia, Wei, Shen, Yang, Chen, Zhu, Chen, Sai-Juan
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801077/
https://ncbi.nlm.nih.gov/pubmed/24082129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315558110
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