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Discovery of novel chemoeffectors and rational design of Escherichia coli chemoreceptor specificity

Bacterial chemoreceptors mediate chemotactic responses to diverse stimuli. Here, by using an integrated in silico, in vitro, and in vivo approach, we screened a large compound library and found eight novel chemoeffectors for the Escherichia coli chemoreceptor Tar. Six of the eight new Tar binding co...

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Detalhes bibliográficos
Main Authors: Bi, Shuangyu, Yu, Daqi, Si, Guangwei, Luo, Chunxiong, Li, Tongqing, Ouyang, Qi, Jakovljevic, Vladimir, Sourjik, Victor, Tu, Yuhai, Lai, Luhua
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801017/
https://ncbi.nlm.nih.gov/pubmed/24082101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306811110
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