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Discovery of novel chemoeffectors and rational design of Escherichia coli chemoreceptor specificity
Bacterial chemoreceptors mediate chemotactic responses to diverse stimuli. Here, by using an integrated in silico, in vitro, and in vivo approach, we screened a large compound library and found eight novel chemoeffectors for the Escherichia coli chemoreceptor Tar. Six of the eight new Tar binding co...
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3801017/ https://ncbi.nlm.nih.gov/pubmed/24082101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1306811110 |
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