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Activation of MRTF-A–dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing
Myocardin-related transcription factors (MRTFs) regulate cellular contractility and motility by associating with serum response factor (SRF) and activating genes involved in cytoskeletal dynamics. We reported previously that MRTF-A contributes to pathological cardiac remodeling by promoting differen...
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Main Authors: | , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3801009/ https://ncbi.nlm.nih.gov/pubmed/24082095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316764110 |
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