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Activation of MRTF-A–dependent gene expression with a small molecule promotes myofibroblast differentiation and wound healing

Myocardin-related transcription factors (MRTFs) regulate cellular contractility and motility by associating with serum response factor (SRF) and activating genes involved in cytoskeletal dynamics. We reported previously that MRTF-A contributes to pathological cardiac remodeling by promoting differen...

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Detalhes bibliográficos
Main Authors: Velasquez, Lissette S., Sutherland, Lillian B., Liu, Zhenan, Grinnell, Frederick, Kamm, Kristine E., Schneider, Jay W., Olson, Eric N., Small, Eric M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3801009/
https://ncbi.nlm.nih.gov/pubmed/24082095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1316764110
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