Influenza Virus Specific CD8(+) T Cells Exacerbate Infection Following High Dose Influenza Challenge of Aged Mice

Influenza viruses cause severe illnesses and death, mainly in the aged population. Protection afforded by licensed vaccines through subtype-specific neutralizing antibodies is incomplete, especially when the vaccine antigens fail to closely match those of the circulating viral strains. Efforts are u...

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Autors principals: Parzych, E. M., DiMenna, L. J., Latimer, B. P., Small, J. C., Kannan, S., Manson, B., Lasaro, M. O., Wherry, E. J., Ertl, H. C.
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2013
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800650/
https://ncbi.nlm.nih.gov/pubmed/24187666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/876314
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