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Quantifying Changes in the Cellular Thiol-Disulfide Status during Differentiation of B Cells into Antibody-Secreting Plasma Cells

Plasma cells produce and secrete massive amounts of disulfide-containing antibodies. To accommodate this load on the secretory machinery, the differentiation of resting B cells into antibody-secreting plasma cells is accompanied by a preferential expansion of the secretory compartments of the cells...

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Detalhes bibliográficos
Main Authors: Hansen, Rosa E., Otsu, Mieko, Braakman, Ineke, Winther, Jakob R.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800581/
https://ncbi.nlm.nih.gov/pubmed/24223594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2013/898563
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