Omeprazole and PGC-formulated heparin binding epidermal growth factor normalizes fasting blood glucose and suppresses insulitis in multiple low dose streptozotocin diabetes model: Omeprazole & growth factor with nanocarrier for Type 1 Diabetes

PURPOSE: Our objective was to develop novel nanocarriers (protected graft copolymer, PGC) that improve the stability of heparin binding EGF (HBEGF) and gastrin and then to use PGC-formulated HBEGF (PGC-HBEGF) and Omeprazole (+/− PGC-gastrin) for normalizing fasting blood glucose (FBG) and improving...

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Main Authors: Castillo, Gerardo M., Nishimoto-Ashfield, Akiko, Banerjee, Aryamitra A., Landolfi, Jennifer A., Lyubimov, Alexander V., Bolotin, Elijah M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800254/
https://ncbi.nlm.nih.gov/pubmed/23793991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-013-1112-6
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