Novel Oncogenic PDGFRA Mutations in Pediatric High-Grade Gliomas

The outcome for children with high-grade gliomas (HGG) remains dismal, with a two-year survival rate of only 10–30%. Diffuse intrinsic pontine glioma (DIPG) comprise a subset of HGG that arise in brainstem almost exclusively in children. Genome-wide analyses of copy number imbalances previously show...

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Hlavní autoři: Paugh, Barbara S., Zhu, Xiaoyan, Qu, Chunxu, Endersby, Raelene, Diaz, Alexander K., Zhang, Junyuan, Bax, Dorine A., Carvalho, Diana, Reis, Rui M., Onar-Thomas, Arzu, Broniscer, Alberto, Wetmore, Cynthia, Zhang, Jinghui, Jones, Chris, Ellison, David W., Baker, Suzanne J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800209/
https://ncbi.nlm.nih.gov/pubmed/23970477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-13-1491
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