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Alternative splicing of exon 3 of the human growth hormone receptor is the result of an unusual genetic polymorphism.

Two isoforms of the human growth hormone receptor (hGHR), which differ in the presence (hGHRwt) or absence (hGHRd3) of exon 3, are expressed in the placenta. Specifically, three expression patterns are observed: only hGHRwt, only hGHRd3, or an approximately 1:1 combination of both isoforms. We inves...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Stallings-Mann, M L, Ludwiczak, R L, Klinger, K W, Rottman, F
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1996
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC38002/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8901592/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.22.12394
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