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Inhibition of endogenous activated protein C attenuates experimental autoimmune encephalomyelitis by inducing myeloid-derived suppressor cells()

Activated protein C (APC) is an anti-coagulant involved in the interactions between the coagulation and immune systems. APC has broad anti-inflammatory effects mediated through its ability to modulate leukocyte function and confer vascular barrier protection. We investigated the influence of APC on...

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Detalhes bibliográficos
Main Authors: Alabanza, Leah M., Esmon, Naomi L., Esmon, Charles T., Bynoe, Margaret S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800123/
https://ncbi.nlm.nih.gov/pubmed/23997223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202556
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