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Gentamicin administration on the stapes footplate causes greater hearing loss and vestibulotoxicity than round window administration in guinea pigs

Clinically, gentamicin has been used extensively to treat the debilitating symptoms of Mèniére’s disease and is well known for its vestibulotoxic properties. Until recently, it was widely accepted that the round window membrane (RWM) was the primary entry route into the inner ear following intratymp...

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Detalhes bibliográficos
Main Authors: King, E.B., Salt, A.N., Kel, G.E., Eastwood, H.T., O’Leary, S.J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800104/
https://ncbi.nlm.nih.gov/pubmed/23899413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heares.2013.07.013
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