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Type 2 innate lymphoid cells constitutively express arginase-I in the naïve and inflamed lung

Arg1 is produced by AAMs and is proposed to have a regulatory role during asthma and allergic inflammation. Here, we use an Arg1 reporter mouse to identify additional cellular sources of the enzyme in the lung. We demonstrate that ILC2s express Arg1 at rest and during infection with the migratory he...

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Библиографические подробности
Главные авторы: Bando, Jennifer K., Nussbaum, Jesse C., Liang, Hong-Erh, Locksley, Richard M.
Формат: Artigo
Язык:Inglês
Опубликовано: Society for Leukocyte Biology 2013
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800063/
https://ncbi.nlm.nih.gov/pubmed/23924659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0213084
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