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Differential regulation of lymphopoiesis and leukemogenesis by individual zinc fingers of Ikaros

C2H2 zinc fingers are found in several transcriptional regulators in the immune system. However, these proteins usually contain more fingers than are needed for stable DNA binding, suggesting that different fingers regulate different genes and functions. Mice lacking finger 1 or finger 4 of Ikaros e...

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Autors principals: Schjerven, Hilde, McLaughlin, Jami, Arenzana, Teresita L., Frietze, Seth, Cheng, Donghui, Wadsworth, Sarah, Lawson, Gregory W., Bensinger, Steven J., Farnham, Peggy J., Witte, Owen N., Smale, Stephen T.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3800053/
https://ncbi.nlm.nih.gov/pubmed/24013668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2707
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