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Management of Reproductive Health in Cowden Syndrome Complicated by Endometrial Polyps and Breast Cancer

BACKGROUND: Cowden syndrome is an autosomal-dominant condition associated with mutations in the tumor suppressor gene PTEN. Gynecologic malignancies are common with a 5–10% risk of endometrial cancer and 25–50% risk of breast cancer. CASE: A 37-year-old woman with a history of breast cancer, other n...

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Detalhes bibliográficos
Main Authors: Kalin, Asli, Merideth, Melissa A., Regier, Debra S., Blumenthal, Gideon M., Dennis, Phillip A., Stratton, Pamela
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799979/
https://ncbi.nlm.nih.gov/pubmed/23344409
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