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Mitochondrial DNA Copy Number and Exposure to Polycyclic Aromatic Hydrocarbons

BACKGROUND: Increased mitochondrial DNA copy number (mtDNAcn) is a biological response to mtDNA damage and dysfunction predictive of lung cancer risk. Polycyclic aromatic hydrocarbons (PAHs) are established lung carcinogens and may cause mitochondrial toxicity. Whether PAH exposure and PAH-related n...

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Detalhes bibliográficos
Main Authors: Pavanello, Sofia, Dioni, Laura, Hoxha, Mirjam, Fedeli, Ugo, Mielzynska-Švach, Danuta, Baccarelli, Andrea A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799962/
https://ncbi.nlm.nih.gov/pubmed/23885040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-13-0118
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