Chemical Castration of melanoma patients does not increase the frequency of tumor-specific CD4 and CD8 T cells after peptide vaccination

Peptide vaccination against tumor associated antigens (TAA) remains one of the most common methods of immunization in cancer vaccine clinical trials. While peptide vaccination has been reported to increase circulating antigen-specific T-cells, they have had limited clinical efficacy and there is a n...

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Bibliographische Detailangaben
Hauptverfasser: Vence, Luis, Wang, Chiyu, Pappu, Himabindu, Anson, Ryan, Patel, Tejal A., Miller, Priscilla, Bassett, Roland, Lizee, Gregory, Overwijk, Willem W., Komanduri, Krishna, Benjamin, Cara, Alvarado, Gladys, Patel, Sapna P., Kim, Kevin, Papadopoulos, Nicholas E., Bedikian, Agop Y., Homsi, Jade, Hwu, Wen-Jen, Boyd, Richard, Radvanyi, Laszlo, Hwu, Patrick
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799876/
https://ncbi.nlm.nih.gov/pubmed/23603862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31829419f3
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