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Broadening roles for FMRP; Big news for Big Potassium (BK) channels
FMRP is an RNA-binding protein that negatively regulates translation,which is lostin Fragile X syndrome. In this issue, Deng et al demonstrate a novel translation-independent function for FMRP as a regulator of presynaptic BK channels that modulate the dynamics of neurotransmitter release.
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2013
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| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3799860/ https://ncbi.nlm.nih.gov/pubmed/23439114 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2013.02.001 |
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