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ASIC1a-Specific Modulation of Acid-Sensing Ion Channels in Mouse Cortical Neurons by Redox Reagents

Acid-sensing ion channel (ASIC)-1a, the major ASIC subunit with Ca(2+) permeability, is highly expressed in the neurons of CNS. Activation of these channels with resultant intracellular Ca(2+) accumulation plays a critical role in normal synaptic plasticity, learning/memory, and in acidosis-mediated...

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Bibliografiske detaljer
Main Authors: Chu, Xiang-Ping, Close, Natasha, Saugstad, Julie A., Xiong, Zhi-Gang
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3799800/
https://ncbi.nlm.nih.gov/pubmed/16707785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0938-06.2006
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